Web exploitation and web shells are some of the most common entry points in the current threat landscape. Web servers provide an external avenue directly into your corporate network, which often results in web servers being an initial intrusion vector or mechanism of persistence. Monitoring for exploitation and web shells should be a high priority for all networks, and while these detection techniques are targeted towards malicious IIS modules, a lot of these techniques will also provide general web shell detections.
IIS modules and the creation of persistent backdoors by malicious IIS modules has recently been addressed in the Microsoft Security blog titled Malicious IIS modules creating persistent backdoors. In this blog by Microsoft Detection and Response Team (DART) aims to provide further guidance on detecting malicious IIS modules and other capabilities (such as logging) that you can use during your own investigations.
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Source: Microsoft